Fig 1: Chrysin inhibits the expression of downstream malignant effectors via DGKα/FAK complex. (A)–(L) The indicated control or DGKα shRNA or 1 μmol/L PF562271-incubated ESCC cells were treated with 50 μmol/L chrysin. The intratumoral expression of C-MYC (A), cyclin D1 (B), survivin (C), SOX2 (D), NANOG (E), OCT4 (F), BMI1 (G), PKM2 (H), HKII (I), LDHA (J), GLUT1 (K), and the secretion of MMP9 in supernatant (L) were evaluated using quantitative ELISA assay. n.s, no significant difference. Error bars, mean ± SD of five independent experiments.
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